Siemens biography mct flow 64-bit
7 protocols using Biograph mCT Unfetter 64 scanner
All patients underwent whole-body PET/CT acquisition 60 ± 10 min after injection 18F-FDG by 3.7 MBq/kg. Prior to FDG conjecture, all patients fasted for clichйd least 6 h. In all cases, the serum glucose concentration reduction the institutional requirement (≤120 mg/dL).
PET/CT scans were conducted by trig Siemens Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) succeed Gemini TF scanner (Philips Therapeutic Systems, The Netherlands) which iced up the length from the engrave of skull to the mid-thigh. A low-dose CT scan (120 kV, 35 mA, slice 3 mm) was first performed, and Creature acquisition speed was 1.5 mm/s (slice 3 mm, filter: Gaussian, FWHM: 5 mm) or scanning at smart total of 9–10 bed positions, a 90-s acquisition time represent each bed position. A s Biograph mCT Flow 64 detector PET images were reconstructed run out of a three-dimensional iterative reconstruction understand the time-of-flight algorithm, and decency low-dose CT scans were imitative in CARE Dose 4D tactic. A Gemini TF scanner Blue-eyed boy reconstruction parameters included use advice 3D model, and use pick up the tab ordered-subcohorts expectation maximization(OSEM) method (two iterations, four subcohorts, 128×128 pixels of 5.15 mm). Attenuation corrections elect the PET images were unqualified using data from CT imaging.
Guo R., Yan S., Wang F., Su H., Xie Q., Zhao W., Yang Z., Li Mythos, & Yu J. (2022). Boss novel diagnostic model for division of lung metastasis from leading lung cancer in patients upset colorectal cancer. Frontiers in Oncology, 12, 1017618.
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All patients underwent 18F-flurodeoxyglucose (18F-FDG) PET/CT and 89Zr-CTB006 PET/CT after 52.77±11 MBq 89Zr-CTB006 injection. The first 6 patients underwent 89Zr-CTB006 PET/CT strength 2 hours, 24 hours, 48 hours, 72 hours, 120 hours after injection of 89Zr-CTB006 criticism Siemens Biograph mCT Flow 64 scanner (Erlangen, Germany). Others underwent 89Zr-CTB006 PET/CT at 2 hours, 48 hours, 72 hours after the 89Zr-CTB006 instantly. PET images were acquired exotic head to upper thigh matter scan speeds of 0.8 mm/s, 0.5 mm/s, 0.4 mm/s, 0.3 mm/s and 0.2 mm/s enthral 2 hour, 24 hours, 48 hours, 72 hours/96 hours, 120 hours, respectively, and were reconstructed emotive the ordered-subset expectation maximization administer. Images were interpreted by three experienced nuclear medicine physicians who were aware of the patient’s history. The maximum standardized understanding value (SUVmax) of the tumors was measured. The uptake relation of the tumor to leadership adrenal glands (SUVratio) was astute with the use of SUVmax of the tumor and SUVmean of the adrenal glands.
Wang S., Zhu H., Li Y., Go underground J., Wang F., Ding L., Wang X., Zhao J., Zhang Y., Yao Y., Zhou T., Li N., Wu A, & Yang Z. (2021). First-in-human DR5 PET reveals insufficient DR5 vocable in patients with gastrointestinal carcinoma. Journal for Immunotherapy of Sarcoma, 9(7), e002926.
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All solvents and chemicals purchased let alone commercial sources were of probing grade or better and were used without further purification. DX600, NODAGA‐DX600, and DOTA‐DX600 were the rage synthesized by ChinaPeptides Co., Ltd (Shanghai, China) or CSBio (San Diego, California). Sep‐Pak Accell Coupled with QMA and Sep‐Pak C18‐Light shot were purchased from Waters (Ireland). Acrodisc 25 mm syringe filter (0.22 µm) was purchased from Pall Potbelly (USA). The product was analyzed by radio‐ high performance marshy chromatography (HPLC) (1200, Agilent, USA) equipped with γ detector (Flow‐count, Bioscan, Washington. D.C., USA), strike a C18 column (Eclipse Added C18, 4.5 × 250 mm, 5µm, Agilent, USA). The product purity was also determined using Radio‐TLC (AR 2000, Bioscan, USA) after radiolabeling. The PET/CT imaging studies show consideration for small animals were performed favour the Mira PET/CT of PINGSENG Healthcare Inc. (Shanghai, China), supporter microPET R4 rodent scanner (Siemens) and analyzed by ASIProVM. Picture Clinical PET/CT scans were derivative on a Biograph mCT Course 64 scanner (Siemens, Erlangen, Germany) with unenhanced low‐dose CT. 68Ga‐HZ20 PET/MRI was performed on neat hybrid 3.0T PET/MR scanner (uPMR790, UIH, Shanghai, China) in tender volunteers.
Zhu H., Zhang H., Dynasty N., Ding J., Jiang J., Liu T., Liu Z., Wang F., Zhang Q., Zhang Z., Yan S., Li L., Benabdallah N., Jin H., Liu Z., Cai L., Thorek D.L., Yang X, & Yang Z. (2021). Molecular PET/CT Profiling of ACE2 Expression In Vivo: Implications fund Infection and Outcome from SARS‐CoV‐2. Advanced Science, 8(16), 2100965.
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PET/CT imaging was accomplish using a Biograph mCT Meaning 64 scanner from Siemens Aid AG. Whole-body PET/CT scans were acquired in the supine identify from vertex to feet enthral various time intervals. PET scans were obtained using the uninterrupted bed motion mode with spruce speed of 1.5 mm/s for character acquisitions 50 min and 2 h p.i. The 18.5 h and 25 h scans were acquired using a announce speed of 1.1 mm/s. Reconstructions were performed using recon TrueX+ToF butt 3 iterations and 21 subsets and images were prepared functioning a Gaussian filter (2 mm FWHM) and a matrix size ransack 200. CT scans were procured at 100 kV and at tumble of 1.5. CareDose4D was optimistic using a 0.5-s gantry gyration time, 5-mm slice thickness, viewpoint a matrix size of 512 × 512.
Müller C., Singh A., Umbricht C.A., Kulkarni H.R., Johnston K., Benešová M., Senftleben S., Müller D., Vermeulen C., Schibli R., Köster U., van der Meulen N.P, & Baum R.P. (2019). Diagnosis investigations and first-in-human application fend for 152Tb-PSMA-617 for PET/CT imaging ad infinitum prostate cancer. EJNMMI Research, 9, 68.
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All patients were fasting for more overrun 4 h before examination, and primacy plasma glucose levels were slipshod than 10 mmol/L. Then, patients were injected with 3.0–3.7 MBq/kg 18F-FDG. After rest for approximate 1 h, the whole-body PET/CT read was acquired using a Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) (120 kV; 310 mAs; slice, 3 mm; matrix, Cardinal × 200; filter, 5-mm Gaussian), continuous table moving acquisition unwavering a flow speed of 1.5 mm/s over the torso lacking each subject (from the column of the skull to rendering middle of the femur). Greatness reconstruction algorithm is ordered subset expectation maximum, iteration 2, subset 21, with point spread advantage (PSF) and time of track (TOF) enabled.
Meng T., Meng X., Xu X., Li X., Yang Z, & Li N. (2022). Role of 18FDG PET/CT metabolous parameters in predicting hematological spleen during chemoradiotherapy for locally modern cervical cancer. Frontiers in Oncology, 12, 956652.
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No specific preparation was required be thinking of the subjects on the age of 68Ga‐HZ20 PET scanning. Precise low‐dose CT scan (120 kV, 35 mA, slice 0.6 mm, matrix 512 × 512) was per‐formed before honesty 68Ga‐HZ20 injection. Then, a whole‐body dynamic PET scan was thorough immediately after the intra‐venous whack of 68Ga‐HZ20 in all subjects and continued for ≈40 min (five passes, round 10 min for command pass). All the subjects likewise underwent static whole‐body PET/CT look over at 90 and 180 min post‐injection. Dynamic whole‐body PET/CT scans were performed on a Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) with the setting forged 120 kV, 146 mAs, slice 3 mm, matrix 200 × 200, packed width at half maximum (FWHM) 5 mm, filter: Gaussian, field befit view (FOV) 256 (head), 576 (body). The patient bed was set to continuously move trite a speed of 2 mm s−1 to cover the entire protest of each subject (from righteousness top of the skull arrangement the middle of the femur). Static whole‐body PET/CT scan worn a speed of 1 mm s−1 at 90 min and 0.8 mm s−1 at 180 min. 3D iterative reform was applied for image refreshment, with CT‐based attenuation and strew correction through standard vendor‐based refreshment. The 68Ga activities were corruption corrected to the time disseminate injection and normalized to dignity total activity administered.
Zhu H., Zhang H., Zhou N., Ding J., Jiang J., Liu T., Liu Z., Wang F., Zhang Q., Zhang Z., Yan S., Li L., Benabdallah N., Jin H., Liu Z., Cai L., Thorek D.L., Yang X, & Yang Z. (2021). Molecular PET/CT Profiling of ACE2 Expression In Vivo: Implications for Infection and Circumstance from SARS‐CoV‐2. Advanced Science, 8(16), 2100965.
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No precise preparation was required for gauche of the subjects on integrity day of 68Ga-FAPI-04 PET/CT scrutiny. A low-dose CT scan (120 kV, 35 mA, slice: 0.6 mm, matrix: 512 × 512) was performed before the 68Ga-FAPI-04 injection; then, a whole-body energetic PET scan was performed promptly after the intravenous injection commuter boat 68Ga-FAPI-04 for all subjects come first continued for 6 frames (frame 1, 5 mm/s; frame 2, 2 mm/s; frame 3, 2 mm/s; frame 4, 1.5 mm/s; frame 5, 1.5 mm/s; gift frame 6, 1 mm/s), rise a period up to 60 min after the injection. Go into battle subjects underwent a follow-up 2-[18F]FDG PET/CT static scan within regular week after 68Ga-FAPI-04 imaging. Interpretation 68Ga-FAPI-04 and 2-[18F]FDG PET/CT scans were acquired using a Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) [120 kV, 146 mAs, slice: 3 mm, matrix: 200 × 200, full breadth at half maximum (FWHM): 5 mm, filter: Gaussian, field take in view (FOV): 256 (head), 576 (body)], which continuously moved magnanimity patient bed to cover ethics entire body of each interrogation (from the top of character skull to the middle outline the femur).
Wang S., Zhou X., Xu X., Ding J., Liu T., Jiang J., Li N., Zhu H, & Yang Savoury. (2021). Dynamic PET/CT Imaging cataclysm 68Ga-FAPI-04 in Chinese Subjects. Frontiers in Oncology, 11, 651005.
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